|Addictions|| Current Smoker
Environment / Toxicity
Cigarette Smoke Damage
| ||In addition to heart disease, cigarette smoking, with an increased consumption of polyunsaturated fatty acids, is the single major cause of cancer death in the United States. Cigarette smokers have total, overall cancer death rates twice that of nonsmokers. The greater the number of cigarettes smoked, the greater the risk. Smoking alone increases lung cancer risk by as much as 40 times.|
Lab Values - Chemistries
Hypocalcemia or hypercalcemia or normal total calcium level
| ||Hypercalcemia associated with malignancy, commonly is the result of breast or lung cancer and is caused by increased osteoclastic activity within the bone.|
Problem Caused By Being Overweight
| ||Researchers used data from a study of lung cancer patients in New York from 1982 to 1985. They focused on patients who had never smoked, or those who hadn't smoked in the last 10 years, then took into account physical data on patients' heights and weight. Researchers found that study subjects who were at the most extreme levels of obesity had the highest risk of lung cancer. The study is a first for linking being overweight to lung cancer; it has previously been shown to play a role in breast, uterine, and colon cancer.|
Researchers are unsure why being obese plays a role in lung cancer; some researchers suggest it's related to hormones such as higher levels of estrogen and insulin. In addition, being overweight puts an added strain on the lungs, reduces lung capacity, and increases asthma risk. [American Journal of Epidemiology Sept. 2000]
Supplements and Medications
Symptoms - Cancer
History of lung cancer
Symptoms - Environment
Significant/severe diesel exhaust exposure
| ||A preliminary report, still undergoing review by experts, states that "for carcinogenic hazard and risk of cancer over a lifetime, the EPA is recommending that exposure (to diesel exhaust) be viewed as likely to pose a risk at low levels, as well as high levels." The draft report, which can be accessed at the agency's website at www.epa.gov, is based on an overview analysis of dozens of animal- and human-based studies. It explains that the particulate matter found in diesel fumes is very small in diameter and thus able to penetrate deeply into the lungs upon inhalation. The report authors also note that "light-duty diesel engines emit 50-80 times and heavy-duty engines 100-200 times more particulate matter than catalytically equipped gasoline engines."|
Air pollution exposure
| ||Over many years, the danger of breathing soot filled air in polluted cities is comparable to the health risks associated with long term exposure to second hand smoke, according to a new study funded by the NIH and US EPA. The study assessed the impact of particles smaller than 2.5 micrometers, called fine particulate matter, in cities across the United States. Data was gathered from 500,000 adults who were followed from 1982 to 1998 as part of an ongoing cancer study. The study concluded that a 10mcg / cubic meter increase in fine particulate matter caused an 8% increase in the number of deaths from lung cancer. [Environmental News Service March 6, 20002]|
Symptoms - Food - Intake
Vegetable oil consumption
| ||Although smoking has been linked to lung cancer, the risk of developing it may be increased more by fatty acid consumption while smoking, rather than by the smoking itself. Lung cancer was not so much of a problem for smokers until polyunsaturated oils such as corn, safflower and sunflower were added to the diet during the 1950s in the United States. Even among smokers, a low fatty acid diet will reduce the likelihood of getting lung cancer.|
(Lack of) vegetable oil consumption
| ||Although smoking has been linked to lung cancer, the risk of developing it may be increased more by fatty acid consumption while smoking, rather than by the smoking itself. Lung cancer was not so much of a problem for smokers until polyunsaturated oils such as corn, safflower and sunflower were added to the diet during the 1950s in the United States. Even among smokers, a low fatty acid diet will reduce the likelihood of getting lung cancer.|| |
Asthma: A lung disorder marked by attacks of breathing difficulty, wheezing, coughing, and thick mucus coming from the lungs. The episodes may be triggered by breathing foreign substances (allergens) or pollutants, infection, vigorous exercise, or emotional stress.
Calcium: The body's most abundant mineral. Its primary function is to help build and maintain bones and teeth. Calcium is also important to heart health, nerves, muscles and skin. Calcium helps control blood acid-alkaline balance, plays a role in cell division, muscle growth and iron utilization, activates certain enzymes, and helps transport nutrients through cell membranes. Calcium also forms a cellular cement called ground substance that helps hold cells and tissues together.
Cancer: Refers to the various types of malignant neoplasms that contain cells growing out of control and invading adjacent tissues, which may metastasize to distant tissues.
Carcinogen: Any agent that is cancer-causing.
Colon: The part of the large intestine that extends to the rectum. The colon takes the contents of the small intestine, moving them to the rectum by contracting.
EPA: Environmental Protection Agency. Also: Eicosapentanoic Acid. A metabolite of the omega-3 fatty acid alpha-linolenic acid.
Epidemiology: The study of the causes and distribution of disease in human populations.
Estrogen: One of the female sex hormones produced by the ovaries.
Fatty Acids: Chemical chains of carbon, hydrogen, and oxygen atoms that are part of a fat (lipid) and are the major component of triglycerides. Depending on the number and arrangement of these atoms, fatty acids are classified as either saturated, polyunsaturated, or monounsaturated. They are nutritional substances found in nature which include cholesterol, prostaglandins, and stearic, palmitic, linoleic, linolenic, eicosapentanoic (EPA), and decohexanoic acids. Important nutritional lipids include lecithin, choline, gamma-linoleic acid, and inositol.
Hormones: Chemical substances secreted by a variety of body organs that are carried by the bloodstream and usually influence cells some distance from the source of production. Hormones signal certain enzymes to perform their functions and, in this way, regulate such body functions as blood sugar levels, insulin levels, the menstrual cycle, and growth. These can be prescription, over-the-counter, synthetic or natural agents. Examples include adrenal hormones such as corticosteroids and aldosterone; glucagon, growth hormone, insulin, testosterone, estrogens, progestins, progesterone, DHEA, melatonin, and thyroid hormones such as thyroxine and calcitonin.
Hypercalcemia: Excess calcium in the blood.
Insulin: A hormone secreted by the pancreas in response to elevated blood glucose levels. Insulin stimulates the liver, muscles, and fat cells to remove glucose from the blood for use or storage.
Microgram: (mcg): 1/1,000 of a milligram in weight.
Polyunsaturated: Polyunsaturated fats or oils. Originate from vegetables and are liquid at room temperature. These oils are a good source of the unsaturated fatty acids. They include flaxseed with added vitamin B6 (pyridoxine), sunflower oil, safflower oil, and primrose oil.
Selenium: An essential element involved primarily in enzymes that are antioxidants. Three selenium- containing enzymes are antioxidant peroxidases and a fourth selenium-containing enzyme is involved in thyroid hormone production. The prostate contains a selenium-containing protein and semen contains relatively large amounts of selenium. Clinical studies show that selenium is important in lowering the risk of several types of cancers. In combination with Vitamin E, selenium aids the production of antibodies and helps maintain a healthy heart. It also aids in the function of the pancreas, provides elasticity to tissues and helps cells defend themselves against damage from oxidation.
Serum: The cell-free fluid of the bloodstream. It appears in a test tube after the blood clots and is often used in expressions relating to the levels of certain compounds in the blood stream.