In those who experience heartburn made worse by lying down, eating before bed may not be a good idea. Eating your last meal at least 3 hours before bed should reduce the likelihood of reflux at bedtime.
Nearly 50 GERD patients and twice as many "controls" without the disease were given a questionnaire to determine the amount of time they took between finishing dinner and going to bed. Those who went to bed within three hours after eating were 7.5 times more likely to suffer from heartburn. [Yahoo News December 27, 2005]