A clinical study from Zimmerís group in Munich in 1992 showed that D-ribose administration to patients with severe, stable coronary artery disease increased exercise tolerance and delayed the onset of moderate angina. Since this groundbreaking study in coronary artery disease, the benefits of D-ribose have been reported for cardiac surgery recovery, heart failure and neuromuscular disease treatment, restoration of energy to stressed skeletal muscle, and control of free-radical formation in oxygen-deprived tissue.
Supplemental D-ribose absorbs easily and quickly through the gut and into the bloodstream 97% absorption.
Studies have shown that any amount of D-ribose you give to energy-starved cells gives them an energy boost. At the University of Missouri, researcher Ronald Terjung has shown that even very small doses (the equivalent of about 500 mg) of D-ribose increase energy salvage in muscles by more than 100%. Larger doses increase the production of energy compounds by 340-430%, depending on the type of muscle tested, and improve the salvage of energy compounds by up to 650%. Most amazing is that when muscles are supplemented with D-ribose, they continue to add to their energy stores even while they actively work! Until this study was reported, it was thought that muscle energy stores were only refilled in muscles at rest.
An adequate dose of D-ribose usually results in symptom improvement very quickly ó sometimes within a few days. If the initial response is poor, the dose should be increased until the patient feels relief. Logically, the sickest patients stand to gain the most. [http://lef.org/]