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It seems that not all HDL is created equal. If you have too much small particle HDL and insufficient cholesterol ester transfer protein for enlarging these small particles, then there is no cardiovascular benefit provided. Therefore, if you have a family history of early heart disease in your closest relatives, but even a high HDL, you may wish to have the size of HDL particles measured. Larger particles offer protection while smaller ones do not.
Cardiovascular: Pertaining to the heart and blood vessels.
Cholesterol: A waxy, fat-like substance manufactured in the liver and found in all tissues, it facilitates the transport and absorption of fatty acids. In foods, only animal products contain cholesterol. An excess of cholesterol in the bloodstream can contribute to the development of atherosclerosis.
High-Density Lipoprotein: (HDL): Also known as "good" cholesterol, HDLs are large, dense, protein-fat particles that circulate in the blood picking up already used and unused cholesterol and taking them back to the liver as part of a recycling process. Higher levels of HDLs are associated with a lower risk of cardiovascular disease because the cholesterol is cleared more readily from the blood.
Protein: Compounds composed of hydrogen, oxygen, and nitrogen present in the body and in foods that form complex combinations of amino acids. Protein is essential for life and is used for growth and repair. Foods that supply the body with protein include animal products, grains, legumes, and vegetables. Proteins from animal sources contain the essential amino acids. Proteins are changed to amino acids in the body.