The Analyst™

Comprehensive diagnosis of your symptoms


  Premenstrual Syndrome PMS D (Depression)  
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Signs, symptoms and indicators | Conditions that suggest it | Contributing risk factors | Recommendations


This subgroup of PMS is the least prevalent and is relatively rare in its pure form. Its key symptom is depression.


Signs, symptoms & indicators of Premenstrual Syndrome PMS D (Depression):
Symptoms - Mind - Emotional  Unexplained teariness/sadness
  Depression with fatigue

Symptoms - Mind - General

  Short-term memory failure

Symptoms - Reproductive - Female Cycle

  Pre/menstrual depression
 PMS type D is characterized chiefly by depression.

  Poor concentration during cycle

Symptoms - Sleep

  Being a light sleeper
  Unsound sleep
  (Frequent) difficulty falling asleep

Conditions that suggest Premenstrual Syndrome PMS D (Depression):
Symptoms - Reproductive - Female CycleCounter-indicators:
  Being/being post menopausal


  Postmenopausal Status / Issues

Risk factors for Premenstrual Syndrome PMS D (Depression):
Symptoms - Mind - GeneralCounter-indicators:
  Absence of short-term memory loss

Recommendations for Premenstrual Syndrome PMS D (Depression):
Amino Acid / Protein  Tyrosine


Not recommended:
 In patients with PMS Type D, progesterone levels may be elevated. You should have your hormone levels checked prior to any hormone therapy: using progesterone cream may only make symptoms worse.


 Lead blocks the binding of estrogen to receptor sites and but has no effect on progesterone. A chronic magnesium deficiency may be a contributing factor as it results in increased lead absorption and retention, while decreasing resistance to stress. Hair mineral analysis has shown that, in general, PMS patients have higher heavy metal levels and lower magnesium levels than non-PMS controls. Menstrual cramps, irritability, fatigue, depression and water retention have been lessened with magnesium, usually given along with calcium and often with vitamin B6. Magnesium is often at its lowest level during menstruation. Supplementing magnesium in the same amount (or more) as calcium (about 500-1,000mg daily) is currently recommended for premenstrual problems.


  Vitamin B6 (Pyridoxine)
 In one study, women received 50mg per day of vitamin B6 or a placebo for 3 months. Symptoms amongst these women included depression, irritability, tiredness, headache, breast tenderness and swollen abdomen/hands. At this dose depression, irritability and tiredness were the only symptoms to respond and they were reduced by 50%. [Gynecol Obstet Invest 1997;43(2): 120-124]

Weak or unproven link
Strong or generally accepted link
Strongly counter-indicative
May do some good
Likely to help
Reasonably likely to cause problems