The glands that are known to have endocrine function include the pineal, pituitary, thyroid, parathyroid, thymus, adrenal, pancreas, and gonads (testes and ovaries). Other organs of the body are also commonly referred to as “glandulars” when they are taken as supplements. These include extracts of the heart, spleen, prostate, uterus, brain, etc… When many hormone systems are operating at a depressed level, glandular preparations may be combined into one product containing material from many organs and glands.
Glandular therapy refers to the use of animal tissues to try to enhance the function of, or mimic the effect of, the corresponding human tissue. Therefore, if your pituitary gland function is in question, the use of pituitary extracts may be supportive.
There are two basic concepts upon which glandular therapy is based. The first is that “like heals like.” For example, feeding prostate tissue might, in theory, help the body’s prostate gland heal or function better. The second concept is that ingestion of certain glandular tissues will provide the body with hormones or other biologically active substances that are normally secreted by that gland. For almost as long as historic records have been kept, glandular therapy has been an important form of medicine.
While some glandular preparations may be effective orally because of active hormone or enzyme content, the effects of other commercially available glandular products are not known as they have not been studied adequately.
Most glandular products are derived from beef (bovine) sources, with the exception of pancreatic extracts, which are most often derived from pork (porcine). The four most widely known methods of processing are the azeotrophic method, salt precipitation, freeze-drying, and predigestion.
The azeotrophic method begins by quick-freezing the material at well below 0 degrees F, and then washing the material with a powerful solvent (ethylene dichloride) to remove the fatty tissue. The solvent is then distilled off and the material is dried and ground into a powder so that it can be placed in tablets or capsules. Although the azeotrophic method aids in the removal of fat-stored toxins (like pesticides) and toxic heavy metals, it also removes fat-soluble hormones, enzymes, essential fatty acids, and other potentially beneficial materials.
The salt precipitation method involves the maceration of fresh glandular material in a salt and water solution. Like the azeotrophic method, this process also allows the fat-soluble material to be separated out. The benefit of the salt precipitation method is that no toxic solvents are used to remove the fatty material. The down side is that the salt content can be very high, and that some of the potentially beneficial constituents may be removed.
The freeze-drying process involves quickly freezing the glandular material and then placing the material in a vacuum, which removes the water by direct vaporization from its frozen state. The benefits of freeze-drying are that it preserves more of the unaltered protein and enzymes as well as all of the fat-soluble components. Since the fat is not removed, potentially harmful contaminants that accumulate in fat tissue may remain in the product. It is therefore critical that the glands be derived from livestock that have grazed on open ranges that are not sprayed with pesticides or herbicides. The animals should also be free of antibiotics, synthetic hormones, and infection. Some companies only use the glands from newborn animals.
The predigestion method employs the aid of plant and animal enzymes to partially digest or hydrolyze the glandular material. The partially digested material is then passed through a series of filtrations to separate out fat-soluble and large molecules. The purified material is then freeze-dried. This method of extraction is thought to be ideal for certain glandulars, such as liver and thymus, where the polypeptide (small proteins) and other water-soluble fractions are desired.
Live Cell Therapy
A form of cellular therapy has been used by almost every culture since the dawn of mankind. Ingesting tissue, either animal or human with the expectation of acquiring spiritual or physical benefits has been chronicled throughout recorded history.
It was Dr. Kuettner, who in 1912, set the stage for modern Live Cell Therapy. He recommended that glands either be surgically implanted into the patient or cut into small pieces, dissolved in saline solution and injected into the patient. The injection method was all but forgotten until one day Dr. Niehan (in the 1930's) was confronted with a patient that was too ill to be considered for an operation.
Normally he would have surgically implanted the gland, but instead he cut the parathyroid gland of an ox into tiny pieces, dissolved it in a saline solution and injected it into the patient. To his surprise, the benefits of the injection lasted longer than any synthetic hormone, or implant of a surgical graft. Many decades later, the patient was still free from the original disabling symptoms. This (injection approach) was the beginning of Live Cell Therapy as we know it today.
Swiss physician Paul Niehans discovered the beneficial effects of live cell therapy quite by accident. In 1931, Niehans was summoned by a colleague who had accidentally removed a patient's parathyroid glands during the course of thyroid surgery. So vital are these glands to life that there was little chance that the woman could survive the day without them. A successful transplant was the only chance the surgeon had of saving her. So Niehans, who had a reputation for therapeutically transplanting organs and glands, was called in.
On his way to the hospital, Niehans stopped off at the abattoir, where the animals he used in his revitalization experiments were slaughtered. He obtained fresh parathyroid glands from a steer and proceeded to the hospital, fully intending to perform a parathyroid transplant.
However, when Niehans arrived, one look at the patient-who was violently convulsing-told him that there was simply not enough time to perform the operation. The woman would not survive long enough.
But Niehans had an idea. He used a surgical knife to slice the steer's parathyroid glands into finer and finer pieces, taking care not to mash the individual cells. He then mixed the pieces in a saline solution and loaded it into a large hypodermic needle. To the shock and dismay of his colleagues, Niehans injected the mixture into the fatally ill woman.
Immediately, her convulsions ceased. Her condition improved- and continued improving. To everyone's surprise, including Niehan's, she recovered. Niehans wrote, many years later, "I thought the effect would be short-lived, just like the effect of an injection of hormones, and that I should have to repeat the injection. But to my great surprise, the injection of fresh cells not only failed to provoke a reaction but the effect lasted, and longer than any synthetic hormone, any implant or any surgical graft."
Longer indeed. The woman went on to live another 30 years, well into her 90's.
Thus was born cell therapy. At his Clinique La Prairie in Montreaux, Switzerland, Dr. Niehans went on to administer live cell injections to thousands and thousands of patients, including many of the crowned heads, presidents, Pope Pius XII, and several Hollywood stars.
In the 1980's, and with the advent of the bringing of the Niehans system to Mexico (primarily through one of his disciples, W.W. Kuhnau), cellular therapy was fitted into a broader concept by the Bradford Research Institute in conjunction with American Biologics-Mexico, S.A. Medical Center. This broader concept is "individualized, integrated metabolic programs" (IIMP) - a holistically oriented and eclectic multidisciplinary approach to chronic, systemic degenerative diseases.
But in whatever program live cell therapy is used, the treatments are still basically aimed at a combination of endocrinological stabilization, ("hormonal harmonizing," as Dr. Kuhnau calls it), rejuvenation and regeneration. All such treatments consist of the subcutaneous injection of cellular suspensions from embryonic endocrine glands and other tissues, the injections given in rapid sequence in one sitting. The combinations of which kinds of cells to give constitutes not only the "science" but the "art" of live cell therapy the use of thymus, brain and adrenal live cells in muscular dystrophy, or of bone and alveolar cells for arteriosclerosis, for example. While as many as 40 kinds of glandular or tissue cellular suspensions are normally available for live cell therapy, it is rare to give more than six in one day for a single course of treatment.
The combining of live cell injections within a total program of vitamins, minerals, enzymes, amino acids, anti-oxidative substances and dietary manipulation, as advances by the B.R.I.- AB-Mexico effort, began turning in startling results in the 1980's which continue to the present time. The addition of a thorough pre-treatment program to potentiate live cells is a primary element in this new dimension, as pioneered by the B.R.I.
The cellular suspensions provide some results, which may be felt almost immediately and other, more typically, become apparent from three to five months later. And as results settle in, patients almost experience a wide variety of positive responses. Not only do specific pathologies reflect benefits, but such subjective signs as sudden improvement in energy levels, vision, appetite normalization, immunological panels and sexual performance are frequently reported.
Live cells must either be used immediately or preserved in some manner for future use. Freezing and freeze-drying became the two methods for cell preservation, but the specific manner in which cells are frozen and thawed determine whether they will be viable following storage in the frozen state. It is now understood that typical freeze-drying not only ruptures cells, but inactivates cell recognition receptors and liberates much more antigenic material than from whole cells, and that freezing without cryoprotectants and timed-freeze and thaw techniques alters cells, preventing them from targeting the important alpha fetoprotein (AFP) and other cellular materials.
Cell preservation problems have been solved. The B.R.I. is researching advances in the modern techniques of cell culture which promise to replace present-day methods of cell preservation.