Animal studies indicate that pregnenolone may aid in repairing the degeneration of the myelin sheath, the cause of Multiple Sclerosis. Further studies are required to determine if there is any benefit for humans with MS.
Aging can causes a deficiency in pregnenolone and DHEA production. Over the years, medical researchers have discovered pregnenolone is an effective stimulant of the amygdala area of the brain an area which plays a major role in memory retention. While memory enhancment has been documented in animal studies, support for use in humans is still anecdotal. While more study is needed, several experts in the field of natural memory stimulants have called pregnenolone 'the most potent memory enhancer ever found.'