D-glucarate functions by inhibiting the dangerous beta-glucuronidase enzyme, thus protecting the critical “glucuronidation” detoxification mechanism. One example of the importance of glucuronidation can be seen in the risk factors for breast cancer. Excess levels of free estrogens and the beta-glucuronidase enzyme are associated with increased incidence of breast cancer. The beta-glucuronidase enzyme is associated with an increase in the number of estrogen receptors. D-glucarate has been shown to lower estrogen receptors while reducing tumor growth. When breast cells hyper-proliferate in response to excess estrogen stimulation, the risk of breast cancer increases. In men, excess estrogen stimulation in the prostate gland can result in benign enlargement. D-glucurate suppresses the “bad” enzyme beta-glucuronidase, thus helping to protect against the carcinogenic effects of estrogen. This discovery helps explain why those who eat certain types of vegetables and fruits have relatively low rates of cancer.
Calcium-D-Glucarate can help with the following
Key
| May do some good |
Glossary
Enzymes
Specific protein catalysts produced by the cells that are crucial in chemical reactions and in building up or synthesizing most compounds in the body. Each enzyme performs a specific function without itself being consumed. For example, the digestive enzyme amylase acts on carbohydrates in foods to break them down.
Cancer
Refers to the various types of malignant neoplasms that contain cells growing out of control and invading adjacent tissues, which may metastasize to distant tissues.
Estrogen
One of the female sex hormones produced by the ovaries.
Prostate
The prostate gland in men that surrounds the neck of the bladder and the urethra and produces a secretion that liquefies coagulated semen.
Benign
Literally: innocent; not malignant. Often used to refer to cells that are not cancerous.
Carcinogen
Any agent that is cancer-causing.