Hydrazine Sulfate

The largest study of hydrazine sulfate (740 cancer patients in the Soviet Union) found that hydrazine sulfate produced stabilization or regression of the tumor in 50.8% of the patients. Other studies have not found similar results but may have been flawed.

According to Dr. Joseph Gold, who pioneered this use of hydrazine sulfate, there are few side effects – mild numbness of the digits, nausea and slight drowsiness. Nerve inflammation can be cause by long-term use, but this can be diminished or eliminated by taking vitamin B6 or reducing the dose of hydrazine sulfate.

NOTE that it is not approved by the FDA for cancer therapy and, if taken, should be used under the direction of your doctor. If a special diet (discussed below) is not adhered to, it can be useless at best and fatal at worst. Despite the care that must be taken, many people have found it helpful.

Hydrazine sulfate is usually administered orally to cancer patients in 60mg capsules or tablets, approximately one to two hours before meals. It is given at first once per day for several days, then twice, then three or four times daily, depending on the patient’s response and the physician’s judgment. On such a regimen, many terminal and semiterminal patients have derived considerable benefit, although patients in the early stages of the disease derive the most benefit from the treatment.

Approximately half of the patients to whom the drug is properly administered in the early stages of the disease show an almost immediate weight gain and reversal of symptoms; in some instances, the tumor eventually disappears. The common types of cancer most frequently reported to benefit from hydrazine sulfate therapy are recto-colon cancer, ovarian cancer, prostatic cancer, lung (bronchogenic) cancer, Hodgkin’s disease and other lymphomas, thyroid cancer, melanoma, and breast cancer. Some less common types of cancer also benefit.

WARNING! Hydrazine sulfate is a monoamine oxidase (MAO) inhibitor and is incompatible with tranquilizers, barbiturates, alcohol and other central nervous system depressants. Foods high in tyramine, such as aged cheeses and fermented products, are also incompatible with MAO inhibitors. The use of tranquilizers, barbiturates and/or alcoholic beverages with hydrazine sulfate destroys the efficacy of this drug and increases patient morbidity.

Whether hydrazine sulfate should be used in conjunction with other agents seems to be dependent on whether these agents are doing the patient any demonstrable good.” says Dr. Gold. “In the instances in which these agents have been doing good, hydrazine sulfate should be used in conjunction with them. However, and especially with those cases on toxic drugs, in instances in which the drugs have been doing no evident good, it is probably best to withdraw such drugs and use hydrazine sulfate alone.


Hydrazine Sulfate can help with the following


Cancer / Risk - General Measures

Cachexia (wasting) in cancer patients is produced by the cancer cells’ partial metabolism of glucose, which leaves lactic acid as a by-product. The liver expends enormous amounts of the body’s energy converting lactic acid back to glucose. As the cancer grows (and puts out more and more lactic acid) this process is intensified, and the body weakens and wastes away. Hydrazine sulfate works by blocking a liver enzyme that catalyzes the conversion of lactic acid into glucose. This both stops the constant energy drain on the body and robs the tumor of a significant source of energy.

Tumors, Malignant  

Breast Cancer

See the link between Cancer (General) and Hydrazine Sulfate.


Prostate Cancer

See the link between Cancer (General) and Hydrazine Sulfate.


Colon Cancer

See the link between Cancer (General) and Hydrazine Sulfate.


Lung Cancer

See the link between Cancer (General) and Hydrazine Sulfate.


Ovarian Cancer

See the link between Cancer (General) and Hydrazine Sulfate.



See the link between Cancer (General) and Hydrazine Sulfate.


Hodgkin's Lymphoma

See the link between Cancer (General) and Hydrazine Sulfate.


Non-Hodgkin's Lymphoma

See the link between Cancer (General) and Hydrazine Sulfate.


Thyroid Cancer

See the link between Cancer (General) and Hydrazine Sulfate.


May do some good



Refers to the various types of malignant neoplasms that contain cells growing out of control and invading adjacent tissues, which may metastasize to distant tissues.


Symptoms resulting from an inclination to vomit.

Vitamin B6

Influences many body functions including regulating blood glucose levels, manufacturing hemoglobin and aiding the utilization of protein, carbohydrates and fats. It also aids in the function of the nervous system.


The (American) Food and Drug Administration. It is the official government agency that is responsible for ensuring that what we put into our bodies - particularly food and drugs - is safe and effective.


(mg): 1/1,000 of a gram by weight.

Hodgkin's Disease

Cancer of the lymphatic system and lymph nodes.


Thyroid Gland: An organ with many veins. It is at the front of the neck. It is essential to normal body growth in infancy and childhood. It releases thyroid hormones - iodine-containing compounds that increase the rate of metabolism, affect body temperature, regulate protein, fat, and carbohydrate catabolism in all cells. They keep up growth hormone release, skeletal maturation, and heart rate, force, and output. They promote central nervous system growth, stimulate the making of many enzymes, and are necessary for muscle tone and vigor.


A life-threatening type of skin cancer that occurs in the cells (melanocytes) that produce melanin, the pigment found in skin, hair, and the iris of the eyes.

Monoamine Oxidase

(MAO) Enzyme catalyzing the removal of an amine group from a variety of substrates, including norepinephrine and dopamine.


Abbreviation for a breakdown enzyme monoamine oxidase. A MAO inhibitor blocks the action of monoamine oxidase, thus raising the levels of the monoamine neurotransmitters such as norepinephrine, epinephrine, dopamine, and serotonin - which have significant effects on mood and behavior. Epinephrine, norepinephrine and serotonin are normally deactivated by MAO-A while dopamine and phenylethylamine are normally metabolized by MAO-B.

Nervous System

A system in the body that is comprised of the brain, spinal cord, nerves, ganglia and parts of the receptor organs that receive and interpret stimuli and transmit impulses to effector organs.


An amino acid synthesized in the body from the essential amino acid tyrosine that has a sympathomimetic action and is derived from tyrosine.

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