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| Mercury Toxicity / Amalgam Illness |
Last updated: Nov 19, 2009 |
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Mercury Toxicity / Amalgam Illness |
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Signs, symptoms and indicators | Conditions that suggest it | Contributing risk factors | It can lead to... | Recommendations
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Acute mercury poisoning Mercury poisoning differs from the other forms of metal poisoning in that it causes neurological symptoms rather than digestive disorders. The source of mercury poisoning is primarily contamination of food by polluted water containing mercuric compounds from industrial waste or organic mercury contained in some fungicides. Food or feed grains treated with mercury-containing fungicides are a potential source for transmission of the metal through both animal and cereal foods. The onset time is one week or more, at which time the symptoms of numbness, weakness of the legs, spastic paralysis and impaired vision are noted. Blindness and coma are extreme symptoms of the poisoning.
Chronic mercury poisoning The symptoms of low-level, chronic mercury exposure and toxicity can be very general and difficult to diagnose based on symptoms alone. In addition, individuals show varying levels of sensitivity to the presence of mercury: amalgam removal may be very important in the recovery process of one person, while for another it may be best to leave the amalgams in place.
Mercury is usually targeted because it is the most common toxicity that most people have - for example, amalgams in teeth contain over 50% mercury. The remainder is made up of silver and sometimes tin, aluminum and other metals. The mercury escapes the amalgam as a vapor and is breathed into the body of the person carrying the amalgam.
Elemental and inorganic mercury exposure can come from amalgam fillings, burning of coal and medical wastes, and environmental and occupational exposures. While these forms of mercury are toxic, they pale in comparison to the toxicity of methylmercury. Methylmercury is formed through microbial action from inorganic mercury that has deposited in the oceans and lakes and bioaccumulates through the food chain in ever increasing concentrations through the large predatory fish. Seafood contamination is a significant source of organic mercury and a serious concern worldwide.
Two scientists completed a study that involved taking measurements of mercury in cicadas, particularly in areas where there were power plants. Their goal was to use their method as a type of indicator that the soil they were in would become polluted. Researchers cautioned people against eating any kind of insect like cicadas, which surprisingly were the carriers of heavy metals. Further investigations have been initiated to determine whether the mercury concentration in the cicadas came from man-made factors or occurred from natural sources such as soil. [Science Daily June 1, 2004]
There is a web site that you can access calledGotMercury.org. They have a simple, yet handy, calculator that you can use to estimate your mercury risk based upon your weight and current fish consumption.
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Signs, symptoms & indicators of Mercury Toxicity / Amalgam Illness: | |  | | | | Symptoms - Aging | Poor balance | Symptoms - Bowel Movements |
Frequent/occasional/regular painful urge to defecate | Symptoms - Cardiovascular |
Heart racing/palpitations | Symptoms - Food - General |
Weak appetite | Symptoms - General |
Constant fatigue
Poor bodily coordination
Showers cause fatigue
Fatigue on light exertion | Symptoms - Glandular |
(Frequent) cervical node swelling | Swollen lymph nodes in the neck have been associated with known mercury toxicity. Other sites reported include in front of the ear, under the jaw, and on the back of the neck. |
| Symptoms - Head - Eyes/Ocular |
Vision disturbances | Intermittent blurred distance vision is a sign of mercury toxicity. |
Bulging eyes | Marked proptosis (bug eyes), or eye changes typical of hyperthyroidism have been associated with mercury toxicity. |
| Symptoms - Head - Mouth/Oral |
Dark spots on gums
A swollen tongue
Metallic taste in mouth
Coated tongue
Cold sores
Abnormal tastes in mouth
Mouth soreness
Gums that bleed easily | Symptoms - Metabolic |
Low body temperature | Symptoms - Mind - Emotional |
Impatient/hostile disposition
Moodiness
Irritability | Symptoms - Mind - General |
Short-term memory failure
Periods of confusion/disorientation
Being easily excitable | Nervous excitability can be a symptom of mercury toxicity. |
Trouble concentrating
Being an antisocial person | Symptoms - Muscular |
Tender muscles | Symptoms - Nails |
Moving white lines across nails | All heavy metals cause Mees' lines on the nails. These usually begin a few months after significant exposure starts and may be useful in identifying the source of exposure - dental amalgams or some unrecognized source - if you remember when they started. |
| Symptoms - Reproductive - Female Cycle |
Unexplained missed periods | Symptoms - Skeletal |
Joint pain/swelling/stiffness | Symptoms - Skin - General |
Diminished perspiration |
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Conditions that suggest Mercury Toxicity / Amalgam Illness: | |  | | | | Allergy | Allergy / Intolerance to Foods (Hidden) | Circulation |
Cardiomyopathy | Mercury levels in the heart tissue of individuals who died from Idiopathic Dilated Cardiomyopathy (IDCM) were found to be on average 22,000 times higher than in individuals who died of other forms of heart disease. [J Amer Coll Cardiology v33(6) pp.1578-1583,1999] |
Angina | Mercury poisoning may be causing chest pain or angina, especially in anyone under age 45. |
| Digestion |
Sensitive Teeth
Diarrhea
Constipation
Bad Breath (Halitosis) | Immunity |
Chronic Fatigue / Fibromyalgia Syndrome
Weakened Immune System | In vitro studies suggest that even low, environmentally relevant exposure levels of mercury, which are not toxic, still contribute to immune dysfunction by interfering with proper lymphocyte functioning. [Scand J Immunol 50(3): pp.233-241] |
Canker Sores (Aphthous Ulcers) | Infections |
Yeast / Candida
Pharyngitis | Lab Values |
Elevated Total Cholesterol | Elevated total cholesterol greater than 270mg may be associated with mercury toxicity. |
| Mental |
Poor Memory | Short term memory loss is initially the most common complaint associated with mercury toxicity. |
Depression
Anxiety
Panic Attacks | Metabolic |
Hypoglycemia | Heavy metals such as mercury, cadmium, lead and thallium poison the glucose metabolizing catalysts, thus reducing the flow of energy throughout the body. It is interesting to note that the symptoms of heavy metal poisoning are similar to symptoms associated with hypoglycemia i.e. hyperactivity, mood swings, manic depressive behavior, poor concentration and impulsive and unpredictable behavior. |
Headaches
Tinnitus
Insomnia | Musculo-Skeletal |
Muscle Cramps / Twitching | Unusual tics or twitching of facial muscles have been associated with mercury toxicity, as well as with muscle cramps in cases of high occupational exposure to mercury. |
| Nervous System |
Neuritis/Neuropathy
Tremors | Organ Health |
Diverticular Disease
Vertigo
Kidney Weakness / Disease | Kidney disease, including kidney failure, is a possible symptom of mercury toxicity. A yearly or more frequent mercury detox program is advised as long as this is a suspected or confirmed problem. |
| Pain |
Low Back Pain / Problems | Mercury toxicity can cause low back pain when it is stored in the sensory ganglia near the low back. |
| Risks |
Increased Risk of Alzheimer's / Dementia | Part of the increase in the incidence of Alzheimer's disease may be due to mercury exposure from mercury amalgam fillings, especially those high in copper content. [Environ Contam Toxicol 2001;67. pp.800 806] |
| Skin-Hair-Nails |
Night Sweats | This symptom may be one of many associated with mercury toxicity. |
Dry skin | Exceptionally dry skin has been associated with mercury toxicity. |
Cold Hands and Feet
Male Hair Loss | Mercury toxicity can cause hair loss. |
Female Hair Loss | Mercury toxicity can cause hair loss. |
| Symptoms - Environment | Counter-indicators:
Being free of mercury toxicity | Symptoms - Head - Eyes/Ocular |
Bulging eyes from hyperthyroidism | Marked proptosis (bug eyes), or eye changes typical of hyperthyroidism have been associated with mercury toxicity. |
| Symptoms - Head - Nose |
Nasal congestion | Mild nasal congestion / stuffy nose can be a sign of mercury toxicity. |
| Uro-Genital |
Female Infertility | Researchers in Hong Kong compared mercury levels in fertile and infertile couples. The results were as follows:
Fertile men 15% with high mercury, Infertile men 35% with high mercury Fertile women 3.8% with high mercury, Infertile women 23% with high mercury
So for infertile men, the chance of mercury toxicity over fertile men was 2.3 times higher and for women, 6 times higher. They recorded how much seafood the couples consumed and found that those eating more seafood tended to have higher blood mercury levels. [Fertility and Sterility, 78: 2, August 2002, pp. 426-428] |
Nocturia |
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Risk factors for Mercury Toxicity / Amalgam Illness: | |  | | | | Childhood | Early/late/delayed puberty onset
Late/delayed/early puberty onset | Metabolic |
Bruxism (Clenching/Grinding Teeth) | People with mercury amalgam fillings who grind their teeth or chew gum can suffer additional mercury release. |
| Supplements and Medications | Counter-indicators:
Heavy metal detoxification use | Symptoms - Food - Intake |
Eating/little mercury contaminated fish
Counter-indicators:
Not eating mercury containing fish | Symptoms - Head - Mouth/Oral |
(Much) past amalgam filling removal
Having amalgam fillings
Poorly-removed amalgams
Counter-indicators:
Carefully-removed amalgams
Not having any/having amalgam fillings | Symptoms - Mind - General | Counter-indicators:
Absence of short-term memory loss | Symptoms - Muscular |
History of tender muscles |
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Mercury Toxicity / Amalgam Illness can lead to: | |  | | | | Circulation | Cardiomyopathy | Mercury levels in the heart tissue of individuals who died from Idiopathic Dilated Cardiomyopathy (IDCM) were found to be on average 22,000 times higher than in individuals who died of other forms of heart disease. [J Amer Coll Cardiology v33(6) pp.1578-1583,1999] |
| Mental |
Schizophrenia | Mercury toxicity can cause mental symptoms like shyness, irritability, apathy and depression, psychosis, mental deterioration, and anorexia. |
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Recommendations for Mercury Toxicity / Amalgam Illness: | |  | | | | Amino Acid / Protein | Cysteine / N-acetyl-cysteine (NAC) | The ability of NAC to enhance methylmercury excretion when given orally, its relatively low toxicity, and its wide availability in the clinical setting indicate that it may be an ideal therapeutic agent for use in methylmercury poisoning. [Environ Health Perspectives, 1998, 106(5): pp.267-71] Earlier concerns over NAC causing mercury to accumulate in the brain and kidneys, as can occur with L-cysteine, now appear to be unfounded. The initial concerns were opinions only, based on L-cysteine research, not NAC research. Still, some clinicians feel that symptom worsening occurs with the use of large doses of NAC (over 300mg per day), especially if they already have elevated levels of L-cysteine. If L-cysteine levels are elevated, cystiene containing products like protein powders should be avoided. |
Glutathione | One of the body's normal mechanisms for dealing with heavy metals involves glutathione and normal levels of this protein should thus be ensured. The rate-limiting precursors are the amino acids cysteine (or N-acetyl-cysteine) and glutamine. |
| Botanical |
Chlorella / Algae Products | Using large doses of chlorella facilitates fecal mercury excretion. After the intestinal mercury burden is lowered by other means, mercury will more readily migrate into the intestine from other body tissues where chlorella will aid in its removal. |
Garlic | Dental |
Dental Metal Removal | Dental amalgam removal is an important first step in reducing your ongoing exposure to mercury. |
| Detoxification |
Heavy Metal Detoxification / Avoidance | Diet |
High/Increased Fiber Diet | Sodium alginate as well as other gel-forming fibers have been shown to inhibit heavy metal uptake in the gut. |
High/Increased Protein Diet | See the link between Heavy Metal Toxicity and Increased / High Protein Diet. A low carbohydrate diet is recommended. |
Grain-free Diet | See the link between Heavy Metal Toxicity and Increased / High Protein Diet. |
Cilantro | Cilantro may help mobilize heavy metals from the brain and central nervous system. |
Not recommended:
Increased Fish Consumption | There is increasing concern over fish which are being found to contain significant levels of mercury. These potentially dangerous levels are coming from fish eating smaller fish - methyl mercury bio-accumulates over time. The large predator fish, such as swordfish/marlin, ahi (yellow fin tuna), king mackerel, shark (often sold as imitation crab), and tilefish have the highest accumulations because they are at the top of the food chain (well, almost!). Many people who consume significant amounts of these fish are showing very elevated levels of mercury in their hair. The FDA is currently recommending most other fish as safe for consumption at amounts of 1kg per week or less.
Mercury enters the environment naturally and through industrial pollution. Cutting back on seafood is a way of cutting down on blood mercury levels, but the benefits of seafood, including omega-3 fatty acids and selenium, should be balanced against the mercury risk.
The U.S. Environmental Protection Agency’s recommended reference dose, or level below which exposures are considered harmless, of mercury in the blood is 5.8 micrograms per liter. The average level of mercury in the women's blood in this particular study, was about one microgram per liter, well below the reference dose.
However, about 8% of the women had levels that above the reference dose. Further, women who ate at least three servings of fish during the 30 days prior to the study had mercury levels of close to two micrograms per liter - four times higher than those of women who did not eat fish.
Adult women had three times higher blood mercury levels than children, partly because adults tend to eat more fish than children, according to researchers.
Fish such as haddock, tilapia, salmon, cod, pollock and sole, as well as most shellfish tend to be relatively low in methylmercury, according to researchers. [JAMA April 2, 2003;289: pp.1667-1674] |
| Lab Tests/Rule-Outs |
Test Hair Analysis | Hair analysis is a reasonable and inexpensive first step toward diagnosing heavy metal toxicity. |
Test for Heavy Metals | Mineral |
Selenium | Selenium is able to combine with metals such as cadmium and mercury to reduce their toxicity. |
Molybdenum | Molybdenum may be useful in the treatment of certain cardiovascular conditions, asthma, allergies and mercury toxicity. |
Sulfur | Mobilization AND excretion are required for mercury detoxification. Consuming foods high in sulfur such as garlic, onions, beans, and eggs or supplemental sulfur in the form of MSM can help move mercury around but it is only bound loosely and caution is advised. There have been reported cases of reversible cataract development from individuals mobilizing mercury without excreting it. Consult a qualified doctor for a detoxification protocol appropriate for you. |
| Nutrient |
Alpha Lipoic Acid | Sources of sulfur such as alpha lipoic acid, MSM and garlic are helpful for protection against heavy metals in general and specifically useful in mercury toxicity. Alpha lipoic acid should not be used alone, as it only mobilizes mercury with a weak bond. Without additional chelators present, such as DMPS or DMSA, the mercury may just redistribute elsewhere in the body instead of being removed. |
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KEY |  | Weak or unproven link |  |  | Strong or generally accepted link |  |  | Proven definite or direct link |  |  | Strongly counter-indicative |  |  | Very strongly or absolutely counter-indicative |  |  | May do some good |  |  | Likely to help |  |  | Highly recommended |  |  | May have adverse consequences |
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