MSM (methylsulfonylmethane) is an odorless, essentially tasteless, white crystalline chemical demonstrating usefulness as a dietary supplement. MSM is a naturally occurring nutrient, a sulfur compound found in typical human diets and those of virtually all other vertebrates. MSM contributes essential sulfur for the synthesis of connective tissue, enzymes and immunoglobulin production. Sulfur is also an important element in the formation of healthy hair and nails. Research suggests that a minimum concentration in the body may be critical to both maintain normal function and structure.
MSM is a natural component of many fresh fruits, vegetables, seafood and meat. Cow’s milk is a particularly rich source of MSM. However, heat and processing can reduce the MSM quantity in foods. MSM is rated as one of the least toxic substances in biology, similar in toxicity to water and much less toxic than common table salt, for example. It has been widely tested as a food ingredient without any reports of allergic reactions.
It is recommended that first time users start at a low level, taking it with meals and increasing the dose gradually. Later, it can be taken without food. A typical starting recommendation is 250mg per day, increasing to an average therapeutic dose of about 2gm per day.
A single dose of MSM will not usually provide any benefit: MSM needs to be taken for at least 1-2 weeks or even up to 2 months before any results will be seen. People taking MSM may notice additional benefits such as softer skin, harder nails, thicker hair, and softening of scar tissue.
At the Oregon Health Sciences University there have been many observations of what MSM can achieve in the way of health and well-being when taken as a dietary supplement.