Noni (Morinda citrifolia) is a fruit with extraordinary healing properties that most North Americans have never heard of. Noni is a small evergreen tree which grows in open coastal regions and in forest areas up to 1,000 feet above sea-level. It can be found from India to Indochina, Malaysia, the Philippines, and the Pacific Islands, like Hawaii.

Preparations of the noni plant has been demonstrated to improve a wide variety of health conditions. Dr Heinicke searched for years to find the active ingredient in noni. After years of research, he eventually identified this ingredient as a new alkaloid – xeronine, which may play a key role in encouraging proper cell function and growth in the body. Xeronine is formed in the large intestine where a chemical reaction occurs between proxeronine and proxeronase – two substances found in abundance in the noni fruit. There are also other substances present which contribute to its rejuvenating qualtity.

Research indicates that noni stimulates the immune system, regulating cell function and cellular regeneration of damaged cells. The fact that noni seems to operate on the very basic and critical cellular level may explain why it is useful for a wide variety of conditions. Limited animal studies have been done and some human cancer studies are underway. Most of the evidence for its use is anecdotal. Since many noni products are sold via multilevel marketing, some caution is necessary regarding exaggerated claims.

For use in the United States, the noni fruit is prepared primarily as a food supplement in juice or capsule form. Most suppliers use only fresh juice which is not allowed to ferment. The plant is very bitter and has an adverse odor. Some preparations are sweetened with fruit juice to make them more palatable. However, this dilutes the juice, requiring that larger amounts be taken. Some products contain only 10% noni juice. The popular belief that the only acceptable form of Noni supplement is as juice is probably due to a misconception put forward for commercial reasons.

The best supplementation of Noni may be in a freeze-dried, powdered form. This freeze-drying process removes only the water without damaging any of this plant’s vital enzymes and avoids the almost intolerable smell.

Thermal processing and dehydration techniques both use methods employing low temperature heat at 110F (43.3C). Thermal processing is the most common in liquid preparations while dehydration processing is used to produce capsules.

Noni may best be taken up to an hour before a meal, as the juice will then pass rapidly through the stomach into the intestines. There seems to be less beneficial action if taken on a full stomach. The pepsin and acid in the stomach destroy the enzyme that liberates xeronine. The juice should not be taken with coffee, tobacco or alcohol as side effects can occur and the beneficial effect of xeronine can be reduced.

Some recommend starting a noni program by consuming up to 32 ounces of 100% juice (or the equivalent) in one week. Thereafter, one to ounces are taken daily. One 500mg capsule is considered the equivalent of 1Tbsp of 100% juice. Thus one bottle of capsules (60) equals a 32 ounce bottle of juice. Check the label carefully before buying. There is a lot of competition between companies, which includes less than accurate advertising.


Noni can help with the following


Addictions / Addictive Tendencies

According to Dr. Ralph Heinicke, xeronine is an alkaloid synthesized in the body & plays a key role at cellular level. When we take in foreign alkaloids like nicotine, cocaine, heroin & caffeine, which mimick xeronine’s natural function, the body’s proteins adapt to them & alter the need of xeronine to an unnatural need for foreign alkaloids. To overcome this addiction, flood your body with xeronine just like you originally flooded the body with foreign alkaloid.

At present noni is known to be the best source of proxeronine (a precursor to xeronine). Some addictions may be helped by placing a few drops of noni juice under the tongue every hour. This will release proxeronine straight into the bloodstream from the soft tissue under the tongue. The body does not get addicted to xeronine & thus noni is not addictive.


Current Smoker

Although almost all the evidence of noni use to stop smoking is anecdotal, there is some logical basis to suggest its use may help break the habit. See noni and ‘Addictive Tendencies”.





Environment / Toxicity  

General Detoxification Requirement

In a groundbreaking experiment Dr. Heinicke demonstrated that tetrodotoxin is accepted by the body only when Xeronine was missing. He did this by taking 30 laboratory mice and dividing them into 3 groups of 10 each. He gave an injection of the tetrodotoxin to one group and they all immediately died. Next he gave an injection of an equivalent amount of xeronine to the second group and they all lived. Finally he mixed together the amounts of tetrodotoxin and xeronine he had used with the other 2 groups of mice and injected the third group of mice.

Not only did all 10 of these mice live, but unlike mice would normally do who have received an intestinal injection, they did not curl up in the wood shavings to recover when placed back in their cages. Instead these mice were by appearnace healthy (alert, energetic, curious and active). Yet these mice had just received a lethal dose of the most powerful neurotoxin known to man. This experiment showed that xeronine (made from precursors found in noni) can be an important agent in preventing harm from neurotoxic substances and promoting health.

The Immune System  

Weakened Immune System

Noni protected mice from developing cancer as would be expected in a trial conducted at the University of Hawaii School of Medicine. Noni acted not by killing the cancer cells, but by stimulating their immune system.



Immune System Imbalance (TH2 Dominance)

Noni promotes NK function and immunity against cancer.


Chronic Inflammation

“Some of the best results I’ve seen with noni juice were in patients with inflammation problems such as arthritis, tendonitis, bursitis, or carpal tunnel,” states Dr. Steven Hall, M.D. He feels that noni helps the body regulate itself and thereby control the inflammatory process.








Organ Health  



May do some good
Likely to help


Immune System

A complex that protects the body from disease organisms and other foreign bodies. The system includes the humoral immune response and the cell-mediated response. The immune system also protects the body from invasion by making local barriers and inflammation.


Refers to the various types of malignant neoplasms that contain cells growing out of control and invading adjacent tissues, which may metastasize to distant tissues.


Specific protein catalysts produced by the cells that are crucial in chemical reactions and in building up or synthesizing most compounds in the body. Each enzyme performs a specific function without itself being consumed. For example, the digestive enzyme amylase acts on carbohydrates in foods to break them down.


A hollow, muscular, J-shaped pouch located in the upper part of the abdomen to the left of the midline. The upper end (fundus) is large and dome-shaped; the area just below the fundus is called the body of the stomach. The fundus and the body are often referred to as the cardiac portion of the stomach. The lower (pyloric) portion curves downward and to the right and includes the antrum and the pylorus. The function of the stomach is to begin digestion by physically breaking down food received from the esophagus. The tissues of the stomach wall are composed of three types of muscle fibers: circular, longitudinal and oblique. These fibers create structural elasticity and contractibility, both of which are needed for digestion. The stomach mucosa contains cells which secrete hydrochloric acid and this in turn activates the other gastric enzymes pepsin and rennin. To protect itself from being destroyed by its own enzymes, the stomach’s mucous lining must constantly regenerate itself.


(mg): 1/1,000 of a gram by weight.


(Tbsp) Equivalent to 15cc (15ml).

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