|Amino Acid / Protein|| Taurine
| ||It has been postulated that the equilibrium between the amino acid taurine and inositol gets disturbed by the increasing sorbitol levels caused by hyperglycemia. This means that taurine supplementation is as least as important as inositol supplementation. It required 1.5g/day of supplemental taurine for IDDM subjects to reach the serum taurine levels of non-diabetic control subjects. [Am J Clin Nutr, 1995: 61 (5): pp.1115-19]|
Caution is advised until the use of taurine in diabetics has been clearly defined. Use only a doctor's supervision!
Taurine deficiency is also implicated in the development of diabetic cardiomyopathy. Studies have shown that some animals fed a taurine deficient diet develop a reversible cardiomyopathy. Whereas humans might not be quite that lucky, taurine certainly helps those of them with it. [Jpn Circ J, 1992: 56 (1): pp.95-9]
| ||The amino acid L-carnitine improves insulin sensitivity in type 2 diabetes.|
| ||Diabetics should exercise caution with supplemental glutamine since they have an abnormal glutamine metabolism. An increased production of glucose from glutamine is probably related to excess levels of glucagon, usually seen in diabetics. |
Diabetics also have poor functioning of the retinal glia cells. The diabetic retina is prone to damage through glutamate excitotoxicity, since the glia are not converting enough glutamate to glutamine.
Glandular / Live Cell Therapy
| ||Researchers have found a way of inducing human beta cells, the insulin-producing cells destroyed by diabetes, thus offering hope of new treatments for the disease.|
Nathalie Fiaschi-Taesch, Ph.D., and Todd Bigatel, both of the University of Pittsburgh School of Medicine, and colleagues found that human beta cells contain a significant amount of a protein called cdk-6. The researchers then went on to discover that increasing cdk-6 production using a viral vector carrying the cdk-6 gene caused the beta cells to replicate. Further studies showed that it was possible to enhance replication by increasing the production of another molecule called cyclin D1, which is involved in cell cycle control.
Next, the researchers transplanted some of the engineered human beta cells under the outer layer of a kidney in a diabetic mouse. Study results showed that beta cell replication continued and the mouse�s blood sugar levels returned to normal levels. Removing the cells from the mouse caused the mouse to immediately become diabetic again.
�This work provides proof-of-principle that the production of human beta cells can be stimulated, and that the newly generated cells function effectively both in the lab and in a living animal,� said senior author Professor Andrew Stewart. [University of Pittsburgh Schools of the Health Sciences. January 13th 2009]
2009. A study carried out in Brazil and published in the Journal of the American Medical Association, on the use of adult stems cells to treat diabetes, has found that most of the patients in the study group were partially or wholly healed of the disease after receiving injections of stem cells from their own bone marrow.
The procedure, called autologous nonmyeloablative hematopoietic stem cell transplantation (HSCT), was carried out on 15 patients with type 1 diabetes mellitus (DM). The report on the study stated that most of the patients no longer needed insulin injections after the treatment and were still "insulin free with normal levels of glycated hemoglobin A1c (HbA1c) during a mean 18.8-month follow-up."
"After a mean follow-up of 29.8 months � the majority of patients achieved insulin independence with good glycemic control."
Fish Oil / Krill
| ||Four grams of fish oil per day reduced triglyceride levels and increased favorable HDL-2a and HDL-2b cholesterol levels in 42 patients with type 2 diabetes. [Diabetes Care 2002;25(10): pp.1704-1708]|
However, recent trials suggest that TOO MUCH fish oil could actually worsen diabetic control. In one study, the use of purified EPA and DHA (fatty acids found in fish oil, and made by your body from Omega 3 fats) at 4gm per day over a 6 week period increased the blood sugar in diabetics, without affecting insulin levels. Caution should be exercised regarding consuming TOO MUCH and blood sugar should be monitored closely if using LARGE DOSES of supplemental fish oils. [AJCN, November 2002 Vol. 76, No. 5, pp.1007-1015 ]
CONVENTIONAL DOSES OF FISH OIL SHOULD BE FINE, EVEN IN DIABETICS. The results of a meta-analysis of 18 trials conducted over a 10-year period show that fish oil supplementation for patients with type 2 diabetes lowers triglycerides but has no statistically significant effect on blood sugar control.
Evening Primrose Oil / GLA
| ||It is well documented that the first step in the conversion of the essential fatty acid (EFA) linoleic acid to gamma-linolenic acid (GLA) is broken in diabetics. This is caused by a production deficit of the enzyme delta-6-desaturase. In more severe cases the EFA metabolism is broken in two places, which is caused by a production defict of the delta 5-desaturase enzyme, further down the conversion chain. The result of this broken process is shortage of GLA and its metabolites; prostacyclin and prostaglandins. |
A key nutrient to give is gamma-linolenic acid (GLA). If the EFA metabolism is only broken in one place, then GLA supply can resolve the prostacyclin/prostaglandin deficiency problem. GLA makes the red blood cells more deformable, regenerates veins/capillaries and in the long run encourages nerve growth. It takes 8-10 weeks for the EPO to start having an effect.
| ||Gymnena sylvestre has been used for centuries in India to treat diabetes. It is also useful in weight loss regimens. A typical daily dose is 1 teaspoon (5ml) BID of a 1:1 liquid extract or 8-12gm of whole dried herb taken in 2 or 3 divided doses. This amount can result in lowered insulin requirements, so caution is advised if you are using insulin when starting the use of this herb.|
Gymnena may help restore pancreatic function over time. Long term use is suggested to achieve the benefits, including lowered glycosylated hemoglobin (HgA1c) levels. One study in rats showed a return to normal fasting levels of glucose after 20 - 60 days of daily use, a rise in insulin levels and an increased number of beta cells in the pancreas. [J Ethnopharmacol 1990;30(3): pp. 281-94]
| ||Liu Wei Di Huang Wan 0r Six Flavor Tea Pill is a formula for many yin deficient diseases and the standard formula for diabetes in China. Many people with diabetes have started taking this while monitoring there insulin levels and gradually needed less and less insulin. Sometimes results are fast, sometimes slow, but there is always seem to be results. Sometimes patients become completely free of taking insulin.|
Green / Oolong / BlackTea (Camellia sinensis)
| ||Epigallocatechin gallate (EGCG), a compound found in tea, may reduce the association between high-fructose corn syrup (HFCS) and diabetes, according to researchers from Rutgers University. Stopping the intake of HFCS would be best, but consuming tea does seem to provide a protective effect, if one continues to use HFCS. [Beverage Daily August 28, 2007]|
| ||Atherosclerosis is associated with roughly 80% of all deaths of patients with diabetes. The study - conducted by researchers at the Technion-Israel Institute of Technology - examined the effects of daily consumption of pomegranate juice on the development of atherosclerosis. |
The researchers, led by Professor Michael Aviram of the Technion Faculty of Medicine, found that diabetic patients who drank 6 ounces of pomegranate juice every day for 90 days experienced a lower risk of developing atherosclerosis.
The study's authors concluded that the juice inhibited the uptake of oxidized "bad" LDL cholesterol by immune cells called macrophages - a process that can bring about the development of atherosclerosis.
Though pomegranate juice contains sugars identical to those found in other fruit juices - which can increase blood sugar and exacerbate diabetes - the sugars found in pomegranate juice did not appear to adversely affect the patients, the researchers found.
"In most juices, sugars are present in free - and harmful - forms," said Aviram. "In pomegranate juice, however, the sugars are attached to unique antioxidants, which actually make these sugars protective against atherosclerosis."
Though the study was fairly small - consisting of only 20 participants - it was part of a larger study aimed at proving the beneficial effects of pomegranate juice on cardiovascular diseases and the oxidation of cholesterol.
Chlorella / Algae Products
Ginseng, American (Panax quinquefolium)
| ||American ginseng may help control the blood sugar surge that generally occurs after eating. Researchers tested the effects of American ginseng on 10 non-diabetic adults and nine adults with type 2 diabetes. Diabetics experienced a significant reduction (20 percent) in blood glucose two hours after treatments, regardless of whether they took the herb before or during the meal.|
Cayenne Pepper (Capsicum frutescens)
| ||Cayenne used topically may benefit diabetic neuropathy. However, using it orally can improve circulation in the extremities and help lower blood sugar - two good reasons for using this seasoning in diabetes. Two to four capsules with meals is recommended.|
Cinnamon (Cinnamonum zeylanicum)
| ||A US Department of Agriculture study of 60 type 2 diabetics revealed that one gram of cinnamon taken daily, over a |
course of 40 days, improved management of blood sugar levels, as well as triglyceride and cholesterol levels. Some
of the subjects took three grams of cinnamon per day, and others took six grams per day, but none of the subjects in
these two groups showed an increased benefit over the group that took one gram per day. One gram of cinnamon is less than half a teaspoon.
Researchers continued to monitor the study participants after the 40-day trial, and found that the subjects' overall
blood sugar levels began rising when the cinnamon intake was discontinued.
Cinnamon not only lowers blood glucose levels if you eat if for at least 6 weeks but it keeps lowering your fasting glucose levels for 20 days after that. The cinnamon spice that works is the common form of powder found in every grocery
store and kitchen, and the cinnamon pills but not the cinnamon oil.
Prior to 2003, researchers believed that the active ingredient in cinnamon that lowered blood sugar was a compound called
"methylhydroxychalcone polymer" or MHCP. Predictably, companies rushed to a sell MHCP pills. However, one of the
original cinnamon study's researchers (Dr. Richard Anerdson of the a US Department of Agriculture affliated lab, conducted a further study in 2004 which showed that MHCP was in fact not the active ingredient producing the beneficial effects on blood sugar. The true active agent that gives cinnamon its power to lower blood sugar and cholesterol is "polyphenol type-A polymer".
Ginseng, Korean - Chinese / Asian (Panax ginseng)
| ||A blinded trial found that 200mg of Asian ginseng per day improved blood sugar levels in people with type 2 (non-insulin-dependent) diabetes. [Diab Care 1995;18: pp.1373-5]|
Mistletoe (Viscum album)
| ||Test tube and animal studies suggest that European Mistletoe extracts can stimulate insulin secretion from pancreas cells, and may improve blood sugar levels in people with diabetes. Given both Mistletoe�s tradition around the world for helping people with diabetes, and these promising pre-clinical results, human clinical trials are certainly needed to establish Mistletoe�s potential for this condition.|
Sugars Avoidance / Reduction
| ||No sweets except for fresh fruit should be eaten. Fruit juices and dried fruit should also be limited or avoided.|
Processed Foods Avoidance
| ||Many doctors and researchers agree that the regular consumption of tasty, mostly modern, commercially processed foods is the primary cause of adult-onset diabetes. Consuming anything sweet, regardless of its calorific content, may be sending a signal from the mouth to the brain that more insulin is needed. Refined and overly processed foods, convenience foods, and foods that are high in refined carbohydrates, high Glycemic Index foods, excessive salt and other additives should all be avoided for good health.|
| ||80% of diabetics are overweight. Obesity is associated with cellular resistance to insulin, thus more insulin is required to maintain normal sugar levels. Weight loss in even the slightly overweight diabetic is essential, so regular exercise is an important part of the prescription. Both aerobic and weight training or Nautilus-type exercise should be done on a regular basis to keep a very high muscle-to-fat ratio in the body. The goal is to make the body "lean and mean."|
| ||One study found that 21 of 23 patients on oral medications and 13 of 17 patients on insulin were able to get off of their medications after 26 days on a near-vegetarian diet and exercise program.[Am J Clin Nutr 1990; 51(3): pp.416-20] During two- and three-year follow-ups, most diabetics treated with this regimen have retained their gains. [Diabetes Care 1983;6(3):268-73] The dietary changes are simple, but profound, and they work. Low-fat, vegetarian diets are ideal for diabetics.|
High/Increased Fiber Diet
| ||Any form of fiber will be beneficial, so choose those that you most easily tolerate. Dietary fiber helps prevent and moderate diabetes through its effects on glucose and, subsequently, insulin levels. A diet high in complex carbohydrates and fiber helps prevent excess blood-sugar levels following meals and increases tissue sensitivity to insulin. This is achieved mainly by slowing the emptying of the stomach and thereby reducing insulin secretion.|
When soluble fiber ferments during digestion it produces 'short chain fatty acids' that increase the metabolism of glucose and thus may add to the beneficial effects of dietary fiber on diabetes. Guar and other water-soluble fibers in beans, oats, barley, and fruit are important and are present in large quantities in a plant-based diet.
Researchers at Lund University in Sweden have determined that those who eat the certain grains for breakfast have lower, well-regulated blood sugar throughout the day, even up to and beyond dinner.
Here are the right grains someone with diabetes should eat:
1. Whole-grain barley (this grain worked best)
2. Whole grain rye
3. Other whole grains such as oats
Increased Fish Consumption
| ||Eating fish twice a week may help diabetes patients. By Mary Brophy Marcus, USA TODAY November 3, 2008|
Centering supper around a fish dish at least twice a week might help people with diabetes lower their risk of kidney disease, a study suggests. In the November issue of the American Journal of Kidney Diseases, British researchers analyzed the records of more than 22,300 middle-aged and older English men and women who were part of a large European cancer study. They wanted to examine the effect of eating fish on kidney disease.
The study subjects had answered questionnaires about their diet habits, including how much fish they ate a week, and had provided urine samples, which were analyzed for the presence of a protein called albumin, an indicator of kidney damage.
The researchers reported that of the 517 study subjects who had diabetes (most of whom had type 2), those who on average ate less than one serving of fish each week were four times more likely to have albumin in their urine than people with diabetes who ate fish twice a week. "Protein in the urine is one of the earliest signs of kidney disease, a serious complication of diabetes," says study co-author Amanda Adler, an epidemiologist with the Medical Research Council Epidemiology Unit at Addenbrooke's Hospital in Cambridge.
Adler speculates that the nutrient content of fish may affect kidney function and improve blood glucose control. But what kind of fish makes the biggest health splash wasn't determined.
"We didn't ask about the type of fish people ate, but in this bit of England people eat cod, plaice, haddock, canned tuna. Even fish and chips would have been included," she says.
Susan Spratt, assistant professor of medicine in the division of endocrinology at Duke University Medical Center, says it's too early to recommend diet changes based on the findings, noting that cause and effect are hard to determine in this type of epidemiological study. "People who eat fish might have other healthier habits," she says.
To prove fish could be a kidney disease-fighting factor in diabetes, clinical trials would be required in which people with diabetes ate fish and others did not, she says. "But it wouldn't hurt patients to eat more fish," says Spratt, who recommends fish oil to lower triglycerides in her diabetes patients who do not respond to or tolerate other therapies.
For dinner, stick with low-fat broiled and baked recipes, she says.
Dairy Products Avoidance
| ||When milk consumption patterns were examined across various nations, there was a very strong correlation with the incidence of insulin-dependent diabetes. It may be that milk proteins cause an autoimmune reaction in which the body mistakenly attacks its own insulin-producing cells.|
Low Fat Diet
| ||It is essential that the diabetic avoid concentrated vegetable oils including margarine, olive oil, corn oil, and other fats. Nuts, olives and avocados are also best left out of the diet due to their fat content.|
Fat, in general, is a problem for diabetics. The more fat there is in the diet, the harder time insulin has in getting sugar into the cell. Exactly why this occurs is not clear. But what is clear is that minimizing fat intake and reducing body fat help insulin do its job much better. Modern diabetic treatment programs drastically reduce meats, high-fat dairy products, and oils.
Soy Isoflavones (genistein, daidzein)
| ||Although the mechanism of action is not clear, supplementation with soy protein can reduce insulin resistance, fasting insulin, hemoglobin A1c, total and LDL-cholesterol levels. This was confirmed in a study of 32 postmenopausal women with adult onset diabetes. [Diabetes Care 2002;25(10): pp.1709-1714]|
Increased Fruit/Vegetable Consumption
| ||Eating carbohydrate-containing foods, including some fruits, temporarily raises blood sugar and insulin levels. On the other hand, a diet rich in the soluble fiber found in fruit may lower the risk of type 2 diabetes, despite the high carbohydrate content of most fruit.|
High-fiber supplements, such as pectin from fruit, have been found to improve glucose tolerance in some studies. A review of the research revealed that the extent to which moderate amounts of fiber help people with diabetes in the long term is still unknown, and the lack of many long-term studies has led some researchers to question the importance of fiber in improving diabetes. Nonetheless, most doctors advise people with diabetes to eat a diet high in fiber. Focus should be placed on fruits, vegetables, seeds, oats and whole-grain products.
The diet plan to reverse diabetes and enable patients to eliminate their dependence on drugs is one derived from vegetables, fruits, grains, and legumes. The diabetic, who is even more sensitive to the harmful effects of the modern diet, should take care to consume a natural plant-based diet with an abundance of raw vegetables in the form of large salads every day.
Artificial Sweetener Avoidance
| ||The American Diabetes Association (ADA) is actually recommending this chemical poison to persons with diabetes. According to research conducted by H.J. Roberts, a diabetes specialist, a member of the ADA, and an authority on artificial sweeteners, aspartame:|
1) Leads to the precipitation of clinical diabetes.
2) Causes poorer diabetic control in diabetics on insulin or oral drugs.
3) Leads to the aggravation of diabetic complications such as retinopathy, cataracts, neuropathy and gastroparesis.
4) Causes convulsions.
In a statement concerning the use of products containing aspartame by persons with diabetes and hypoglycemia, Roberts says: "Unfortunately, many patients in my practice, and others seen in consultation, developed serious metabolic, neurologic and other complications that could be specifically attributed to using aspartame products. This was evidenced by:
"The loss of diabetic control, the intensification of hypoglycemia, the occurrence of presumed 'insulin reactions' (including convulsions) that proved to be aspartame reactions, and the precipitation, aggravation or simulation of diabetic complications (especially impaired vision and neuropathy) while using these products.
"�dramatic improvement of such features after avoiding aspartame, and the prompt predictable recurrence of these problems when the patient resumed aspartame products, knowingly or inadvertently."
Roberts goes on to say:
"I regret the failure of other physicians and the American Diabetes Association (ADA) to sound appropriate warnings to patients and consumers based on these repeated findings which have been described in my corporate-neutral studies and publications."
High Fat Diet
High/Increased Protein Diet
| ||A vegetarian type diet, low in rapidly absorbed carbohydrates, is recommended for those with diabetes.|
Conventional Drugs / Information
| ||Many diabetics are able to control their blood sugar levels by natural means alone. When, for whatever reason, this is not possible, insulin use may be needed. The type of insulin and dose will need to be worked out carefully under your doctor's supervision.|
The pharmacokinetics of insulin absorption are influenced by the insulin species, the dose, exercise of the injection site and the interaction of various modified insulin preparations. Human insulin is absorbed more rapidly than animal insulins, however when considering basal insulin requirements, beef and pork insulins have a longer duration of action and for most purposes can be considered peakless when compared with human insulin. Many reports have indicated an increased frequency of hypoglycemia unawareness with human insulin when patients are switched from beef/pork insulins
Metformin (not a type of insulin) is the generic version of Glucophage. Even though it should be chemically identical, many who have tried both find they have less side-effects on the patented form.
If essential fatty acid metabolism is badly broken and the supplementation of GLA (gamma-linolenic acid) will not produce the necessary products in the quantities needed, then also the drug pentoxifylline can be used. Pentoxifylline has a more immediate effect, while EPO (evening primrose oil) is slower, but has a more complete spectrum of effects in managing the fatty acid deficiencies that diabetics suffer from. EPO and pentoxifylline used over a longer time (4 months to 1 year) cause the blood to become thinner - which is not a bad thing for diabetics - but is a bad thing if it is excessive which can lead to bruising and slower wound-healing. Getting the correct balance might require some attention.
2009. Clinical studies demonstrate that SYMLIN, a self-administered injection given prior to meals, helps patients achieve lower blood glucose (sugar) after meals, leading to less fluctuation during the day, and better long-term glucose control (A1C) compared to patients taking insulin alone. In these studies, patients used less mealtime insulin and also had a reduction in body weight compared to patients taking insulin alone. SYMLIN was studied in over 5300 individuals in the clinical program that led to approval by the FDA.
Diabetes is an example of a condition that primarily results from chronically consuming processed foods - the Standard American Diet (SAD). We consume sugars in excess, and because nothing bad happens immediately, think that everything is fine. Insulin resistance, weight gain, and diabetes develop slowly. Even when one generation escapes the consequences, thenext generation will harvest them.
Just like with finances. When spending is out of control, and we spend what we don't have, we are in effect borrowing from the future. The consequences are only being delayed.
As Moses said, "Be sure your sins will find you out." And so it is with the insulin-related conditions. The chickens are coming home to roost.
Not only is our uncontrolled desire for sweets driving this, but food manufacturers, competing for our food dollars, want people to chose their product over others, even to the point of promoting addiction. When it is all about profit and pleasure, there are sure to be unwanted consequences.
The medical and pharmaceutical community is also profit motivated. Very often, the 'solution' to the problem has nothing to with the cause. This becomes reinforced when we desire a quick fix and aren't willing to break free from our pattern of poor choices. Thus we have new drugs to solve problems, without addressing the cause.
As an example, look at all the research being done to discover new marketable drugs to solve the problem of insulin resistance. Here is an article from http://www.diabetesselfmanagement.com/Articles/Diabetes-Definitions/incretin-hormone/.
The solution isn't chemistry, it is choices. Bad choices will always produce bad fruit and good choices will always produce good fruit - eventually.
"A hormone that stimulates insulin secretion in response to meals. The two most important incretin hormones are called glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Understanding how these hormones work is helping to yield new treatments for Type 1 and Type 2 diabetes.
The whole concept of incretin hormones comes from a decades-old observation that orally administered glucose provokes a far greater release of insulin than the same amount of glucose delivered by injection. Scientists postulated that there must be some signal from the gastrointestinal tract (or �gut�) that increases insulin release whenever food is consumed. A considerable amount of evidence now suggests that GLP-1 and GIP are responsible for most of this increased insulin release. Furthermore, scientists have also observed that people with Type 2 diabetes have diminished insulin release in response to meals and have speculated that they may have defects in the release or action of their incretin hormones.
GLP-1 is made in the small intestine and colon and is released in response to food. It stimulates insulin secretion in a glucose-dependent manner�that is, it stimulates insulin secretion only when there is glucose in the bloodstream. GLP-1 has other beneficial effects as well: It delays stomach emptying, which slows the absorption of carbohydrate and the resulting rise in blood glucose level after meals; it curbs appetite; and animal studies have shown that it may promote regeneration of the pancreatic beta cells and fight apoptosis (programmed cell death), improving the survival of existing beta cells.
GIP is made by cells in the upper small intestine and is released when glucose comes in contact with these cells. Like GLP-1, GIP affects the pancreatic beta cells, where it stimulates insulin secretion, and also appears to promote beta cell proliferation and beta cell survival.
Naturally, all of these effects have prompted drug companies and medical researchers to create drugs that act like incretin hormones or affect their biochemical pathways. For example, they have discovered a substance in Gila monster venom called exendin-4, which acts similarly to human GLP-1 but is much longer-acting. Amylin Pharmaceuticals and Eli Lilly and Company developed a synthetic version of exendin-4 called exenatide (brand name Byetta), which received marketing approval in April of 2005 as an adjunctive treatment for Type 2 diabetes that is not adequately controlled by metformin, a sulfonylurea drug (such as glyburide, glipizide, or glimepiride), or both. The manufacturers are continuing to study the effects of exenatide in people with diabetes and are testing a new formulation that needs to be injected only once a week instead of twice a day. Novo Nordisk is testing another long-acting GLP-1 analog called liraglutide in people with Type 2 diabetes, and a number of other drug companies also have GLP-1 analogs under development.
The National Institute of Diabetes and Digestive and Kidney Diseases is sponsoring a clinical trial to study the effects of exenatide in people who have had Type 1 diabetes for several years but whose pancreases still make some insulin. The trial is designed to determine whether exenatide can help the pancreas generate new beta cells and make more insulin.
Researchers have tried infusing GIP into people with Type 2 diabetes, with varying results. In some cases, insulin secretion was increased, but in others, little or no extra insulin was secreted at all.
Other experimental drugs called DPP-IV inhibitors also affect incretin hormone levels. Dipeptidyl peptidase IV (or DPP-IV) is an enzyme that normally breaks down GLP-1 and GIP. A number of pharmaceutical companies are working on DPP-IV inhibitors, which block the action of this enzyme and therefore leave more of the body�s own GLP-1 and GIP in circulation. DPP-IV inhibitors have been shown to improve blood glucose control, enhance the insulin secretory response, and increase insulin sensitivity in animal and human studies. In rats with chemically induced diabetes (a model of Type 1 diabetes), DPP-IV inhibitors increased the number of pancreatic islets and beta cells. More, longer-term studies of DPP-IV inhibitors in humans are now under way."
Beta 1,3 Glucan
| ||Research has demonstrated the anti-diabetic effect of IL-1 cytokine, which increases insulin production resulting in lowering of blood glucose level. Macrophages are the main source of IL-1 in the body and it's production can be boosted by beta-1,3-glucan supplementation. The high rate of atherosclerosis and the additional requirement for antioxidants in diabetic patients, makes supplemental beta-1,3-glucan an obvious choice.|
| ||Aerobic exercise reduces the risk of diabetes and improves the diabetic condition through several different mechanisms.|
| ||Diabetics should control blood sugar and blood pressure closely and should refrain from smoking.|
Test for Hemoglobin A1c
Tests, General Diagnostic
| ||Determination of hemoglobin A1c is valuable for the follow-up of diabetic patients and useful for measuring a diabetic tendency. While blood glucose monitoring is like a snapshot, hemoglobin A1c testing is more like a full length movie - it provides a view of how your blood glucose level has been doing over a period of two to three months. For people who have not undergone any major changes in their lifestyle or diabetes regimen, hemoglobin A1c tests provide a good assessment of long-term blood glucose control.|
For monitoring diabetes, a satisfactory interval for test taking is every third month. It has been shown that well controlled diabetics have a lower incidence of complications. Since costs for treatment of diabetics are high, hemoglobin A1c testing is very cost effective.
| ||This is the most important micronutrient in helping to stabilize blood sugar level. Chromium affect cellular absorption and makes a more effective use of the insulin, but it does not increase the panceas' production of insulin. It has its greatest effect on type 2 diabetes. |
Chromium picolinate at 5000mcg per day over a 3 month period reduced fasting and 2-hour glucose levels as well as reducing insulin requirements in a study of 136 patients with adult-onset diabetes. [Reported at the American Diabetes Association Meeting, June 14-18, 2002. San Francisco, California]
Six months of treatment with chromium picolinate (500 or 1000mcg per day) reduced hemoglobin A1C (HbA1C) and improved lipid profiles in a well-controlled study of 52 patients with type 2 diabetes and HbA1C greater than 8% despite insulin requirements of greater than 50 units/d. Chromium had no effect on insulin requirements. [Effects of chromium treatment in patients with poorly controlled, insulin-treated Type 2 diabetes mellitus. 18th International Diabetes Federation Congress, Paris, August 24-29, 2003]
Multiple Mineral Supplementation
| ||See the link between Diabetes and Multiple Vitamin Supplement.|
| ||In his latest book, The Diabetes Improvement Program: A Doctor's Handbook for Using Foods and Supplements to Slow and Reverse the Complications of Diabetes, Dr. Patrick Quillin shows you how to use 10 super foods to conquer diabetes naturally...without the use of drugs or needles. With his 7-step program, you too can feel better in just three weeks.|
You'll learn how to:
If you are considering insulin, beginning insulin, or have been on it for years but want to improve your control, the answers to your questions are finally here. This book by the authors of Pumping Insulin provides all the information you need to succeed on insulin.
- Normalize your blood sugar
- Boost your energy
- Lose weight
- Eliminate sugar cravings
- Heal cuts faster
- Strengthen your eyesight
- Regain your sense of balance
- Improve circulation
Using Insulin - Everything You Need For Success With Insulin is by John Walsh PA CDE, Ruth Roberts MA, Chandrasekhar Varma MD FACE FACP, and Timothy Bailey MD FACE FACP
The Live Food Factor by Susan Schenck. A 500 page comprehensive guide, not only to the raw food diet, but also to the raw food movement.
Alpha Lipoic Acid
| ||Numerous additional studies have indicated that ALA is useful for the treatment of diabetes mellitus. It stimulates increased glucose utilization in muscle cells and significantly reduces human insulin resistance.|
600mg of alpha lipoic acid tid was found to improve polyneuropathy symptoms in patients with type II diabetes. A maintenance dose as low as 100mg tid may be sufficient to provide benefits. [Diabet Med 1999;16; pp.1040-1043]
| ||Diabetics over-excrete the vitamin inositol, and they therefore have a general shortage of this. It plays a role in the fat metabolism, and may protect nerve fibers from excess glucose.|
| ||Three months of CoQ10 at 100mg bid reduced blood pressure and glycated HbA1c in a well-controlled study of 74 patients with uncomplicated Type 2 diabetes and lipid abnormalities. [Eur J Clin Nutr 2002;56(11): pp.1137-42]|
Oxygen / Oxidative Therapies
Ozone / Oxidative Therapy
Vitamin C (Ascorbic Acid)
| ||Dr. Fred Klenner, MD has used large amounts of Vitamin C for many ailments, and says that diabetics are so deficient they should be considered as having scurvy. Ten grams per day, according to Dr. Klenner, cures many diabetics and enhances their well being in other cases.|
Vitamin C (1000mg per day) and vitamin E (400IU per day) reduced tear nitrite levels, and improved tear function measures in a study of 50 patients with non-insulin dependent diabetes. [ Br J Ophthalmol 2002;86(12): pp.1369-73]
Vitamin B1 (Thiamine)
| ||Study results suggest that taking a high-dose vitamin B1 supplement each day may help diabetics reduce their risk of kidney damage.|
Diabetic nephropathy, or kidney disease, is a common complication of type 2 diabetes. An early indicator of kidney disease is microalbuminuria, where the kidney leaks albumin into the urine. Researchers set out to investigate whether supplementation with vitamin B1 would effect microalbuminuria.
Type 2 diabetics were given 300 milligrams of vitamin B1 (thiamine) each day for three months. Results showed that the vitamin supplement reduced the rate of albumin excretion by 41%. Furthermore, 35% of patients with microalbuminuria saw their urine albumin excretion return to normal after being treated with the vitamin. Thus, suggesting that treatment with high-dose vitamin B1 can reverse the onset of early diabetic kidney disease. [High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study. Diabetologia. Published online December 5th 2008]
| ||Recent research shows that Type II diabetics who consumed foods high in vitamin A were the most efficient insulin users. [Facchini, F., et al. "Relation between dietary vitamin intake and resistance to insulin-mediated glucose disposal in healthy volunteers," Am J of Clin Nutr 63: pp.946-49, June 1996]|
Multiple Vitamin Supplement
| ||The use of a medium potency broad spectrum multiple vitamin and mineral supplement reduced the incidence of infections in diabetics, but not in a control population. [Ann Intern Med 2003;138: pp.365-371]|
| ||Niacinamide improves ATP mitochondrial production in the face of diabetogenic chemicals and thus allows insulin-producing cells of the pancreas to stay alive longer. In one trial, newly diagnosed patients were given niacinamide at 25mg per kg of body weight. This restored the insulin-producing cells of the pancreas in some, slowed the cellular destruction in others and left a number no longer diabetic. Use in diabetic patients should always be monitored by a physician as insulin requirements may change.|
Vitamin B3 (Niacin)
| ||Although niacin increases low levels of high-density lipoprotein cholesterol, which frequently accompany diabetes, past guidelines did not recommend the use of niacin in patients with diabetes because of concerns about adverse effects on glycemic control; however, this was based on limited clinical data. A 2000 study suggests that lipid-modifying dosages of niacin can be safely used in patients with diabetes and that niacin therapy may be considered as an alternative to statin drugs or fibrates for patients with diabetes in whom these agents are not tolerated or fail to sufficiently correct hypertriglyceridemia or low HDL-C levels. [JAMA. 2000;284: pp.1263-1270]|| |